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Stomach (Gastric) Cancer Prevention (PDQ®)

What is prevention?

Cancerprevention is action taken to lower the chance of getting cancer. By preventing cancer, the number of new cases of cancer in a group or population is lowered. Hopefully, this will lower the number of deaths caused by cancer.

To prevent new cancers from starting, scientists look at risk factors and protective factors. Anything that increases your chance of developing cancer is called a cancer risk factor; anything that decreases your chance of developing cancer is called a cancer protective factor.

Some risk factors for cancer can be avoided, but many cannot. For example, both smoking and inheriting certain genes are risk factors for some types of cancer, but only smoking can be avoided. Regular exercise and a healthy diet may be protective factors for some types of cancer. Avoiding risk factors and increasing protective factors may lower your risk but it does not mean that you will not get cancer.

Different ways to prevent cancer are being studied, including:

  • Changing lifestyle or eating habits.

  • Avoiding things known to cause cancer.

  • Taking medicines to treat a precancerouscondition or to keep cancer from starting.


General Information About Stomach Cancer

Stomach (gastric) cancer is a disease in which malignant (cancer) cells form in the stomach.

The stomach is a J-shaped organ in the upper abdomen. It is part of the digestive system, which processes nutrients (vitamins, minerals, carbohydrates, fats, proteins, and water) in foods that are eaten and helps pass waste material out of the body. Food moves from the throat to the stomach through a hollow, muscular tube called the esophagus. After leaving the stomach, partly-digested food passes into the small intestine and then into the large intestine.

Gastrointestinal (digestive) system anatomy; shows esophagus, liver, stomach, large intestine, and small intestine.
The stomach and esophagus are part of the upper digestive system.

See the following PDQ summaries for more information about stomach cancer:

The number of new cases of stomach cancer has remained about the same over the past several years in the United States.

Over the past several years, the number of new cases of stomach cancer in the United States has remained about the same. Men are more than twice as likely to be diagnosed with stomach cancer than women.

Stomach cancer is the fourth most common cancer in the world.

The number of deaths from stomach cancer has decreased over many years, especially in the United States. Black men are more than twice as likely to die from stomach cancer than white men.


Stomach Cancer Prevention

Avoiding risk factors and increasing protective factors may help prevent stomach cancer.

Avoiding cancerrisk factors such as smoking, being overweight, and lack of exercise may help prevent certain cancers. Increasing protective factors such as quitting smoking, eating a healthy diet, and exercising may also help prevent some cancers. Talk to your doctor or other health care professional about how you might lower your risk of cancer.

The following risk factors may increase the risk of stomach cancer:

Smoking

Studies show that smoking is linked with an increased risk of stomach cancer. Avoiding or stopping smoking decreases the risk of stomach cancer. Smokers who stop smoking lower their risk of developing stomach cancer over time.

Helicobacter pylori infection

Studies show that chronicinfection with Helicobacter pylori (H. pylori) bacteria is linked to an increased risk of stomach cancer. When H. pylori infects the stomach over a long time, it may become inflamed and cause changes in the lining of the stomach that can lead to cancer.

Some studies show that treating H. pylori infection with antibiotics lowers the risk of stomach cancer. More studies are needed to find out whether curing H. pylori infection lowers the number of deaths from stomach cancer or keeps changes in the stomach lining, that can lead to cancer, from getting worse.

Salt in the diet

Studies show that eating a diet with a lot of salt may increase the risk of stomach cancer. Many people in the United States now eat less salt, to lower the risk of high blood pressure. This may be why rates of stomach cancer have decreased in the U.S.

The following protective factors may decrease the risk of stomach cancer:

Diet high in fruit and vegetables

Some studies show that eating fruits and vegetables that are high in vitamin C and beta carotene may lower the risk of stomach cancer. Studies also show that whole-grain cereals, carotenoids, green tea, and substances found in garlic may lower the risk of stomach cancer. These studies may have included people whose usual diets were low in nutrients. This change in diet may not have the same effect in people who already eat a healthy diet.

It is not known if changing your diet to include more vegetables, fruits, and whole grains lowers your risk of stomach cancer.

Dietary supplements

Certain vitamins, minerals, and other dietary supplements may help lower the risk of stomach cancer. In China, a study of increased beta carotene, vitamin E, and selenium supplements in the diet showed a lower number of deaths from stomach cancer. The study may have included people who were missing these nutrients in their usual diets. It is not known if increased dietary supplements would have the same effect in people who already eat a healthy diet.

Other studies have not shown that taking dietary supplements such as beta carotene, or vitamin C lowers the risk of stomach cancer.

Cancer prevention clinical trials are used to study ways to prevent cancer.

Cancer preventionclinical trials are used to study ways to lower the risk of certain types of cancer. Some cancer prevention trials are done with healthy people who have not had cancer but who have an increased risk for cancer. Other prevention trials are done with people who have had cancer and are trying to prevent another cancer of the same type or to lower their chance of developing a new type of cancer. Other trials are done with healthy volunteers who are not known to have any risk factors for cancer.

The purpose of some cancer prevention clinical trials is to find out whether actions people take can prevent cancer. These may include eating fruits and vegetables, exercising, quitting smoking, or taking certain medicines, vitamins, minerals, or food supplements.

New ways to prevent stomach cancer are being studied in clinical trials.

Clinical trials are taking place in many parts of the country. Information about clinical trials can be found in the Clinical Trials section of the NCI Web site. Check NCI's list of cancer clinical trials for stomach cancer prevention that are now accepting patients.


Get More Information From NCI

Call 1-800-4-CANCER

For more information, U.S. residents may call the National Cancer Institute's (NCI's) Cancer Information Service toll-free at 1-800-4-CANCER (1-800-422-6237) Monday through Friday from 8:00 a.m. to 8:00 p.m., Eastern Time. A trained Cancer Information Specialist is available to answer your questions.

Chat online

The NCI's LiveHelp® online chat service provides Internet users with the ability to chat online with an Information Specialist. The service is available from 8:00 a.m. to 11:00 p.m. Eastern time, Monday through Friday. Information Specialists can help Internet users find information on NCI Web sites and answer questions about cancer.

Write to us

For more information from the NCI, please write to this address:

  • NCI Public Inquiries Office

  • Suite 3036A

  • 6116 Executive Boulevard, MSC8322

  • Bethesda, MD 20892-8322

Search the NCI Web site

The NCI Web site provides online access to information on cancer, clinical trials, and other Web sites and organizations that offer support and resources for cancer patients and their families. For a quick search, use the search box in the upper right corner of each Web page. The results for a wide range of search terms will include a list of "Best Bets," editorially chosen Web pages that are most closely related to the search term entered.

There are also many other places to get materials and information about cancer treatment and services. Hospitals in your area may have information about local and regional agencies that have information on finances, getting to and from treatment, receiving care at home, and dealing with problems related to cancer treatment.

Find Publications

The NCI has booklets and other materials for patients, health professionals, and the public. These publications discuss types of cancer, methods of cancer treatment, coping with cancer, and clinical trials. Some publications provide information on tests for cancer, cancer causes and prevention, cancer statistics, and NCI research activities. NCI materials on these and other topics may be ordered online or printed directly from the NCI Publications Locator. These materials can also be ordered by telephone from the Cancer Information Service toll-free at 1-800-4-CANCER (1-800-422-6237).


Changes to This Summary (12/09/2010)

The PDQcancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

This summary was completely reformatted and some content was added.


Questions or Comments About This Summary

If you have questions or comments about this summary, please send them to Cancer.gov through the Web site’s Contact Form. We can respond only to email messages written in English.


About PDQ

PDQ is a comprehensive cancer database available on NCI's Web site.

PDQ is the National Cancer Institute's (NCI's) comprehensive cancer information database. Most of the information contained in PDQ is available online at NCI's Web site. PDQ is provided as a service of the NCI. The NCI is part of the National Institutes of Health, the federal government's focal point for biomedical research.

PDQ contains cancer information summaries.

The PDQ database contains summaries of the latest published information on cancer prevention, detection, genetics, treatment, supportive care, and complementary and alternative medicine. Most summaries are available in two versions. The health professional versions provide detailed information written in technical language. The patient versions are written in easy-to-understand, nontechnical language. Both versions provide current and accurate cancer information.

The PDQ cancer information summaries are developed by cancer experts and reviewed regularly.

Editorial Boards made up of experts in oncology and related specialties are responsible for writing and maintaining the cancer information summaries. The summaries are reviewed regularly and changes are made as new information becomes available. The date on each summary ("Date Last Modified") indicates the time of the most recent change.

PDQ also contains information on clinical trials.

A clinical trial is a study to answer a scientific question, such as whether a certain drug or nutrient can prevent cancer. Trials are based on past studies and what has been learned in the laboratory. Each trial answers certain scientific questions in order to find new and better ways to help cancer patients and those who are at risk for cancer. During prevention clinical trials, information is collected about the effects of a new prevention method and how well it works. If a clinical trial shows that a new method is better than one currently being used, the new method may become "standard." People who are at high risk for a certain type of cancer may want to think about taking part in a clinical trial.

Listings of clinical trials are included in PDQ and are available online at NCI's Web site. Descriptions of the trials are available in health professional and patient versions. Many cancer doctors who take part in clinical trials are also listed in PDQ. For more information, call the Cancer Information Service 1-800-4-CANCER (1-800-422-6237).


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